ex2119: Meta-Analysis of Breast Cancer and Lactation Studies

In Sleuth2: Data Sets from Ramsey and Schafer's "Statistical Sleuth (2nd Ed)"

Meta–Analysis of Breast Cancer and Lactation Studies

Description

This data frame gives the results of 10 separate case–control studies on the association of breast cancer and whether a woman had breast–fed children.

Usage

ex2119

Format

A data frame with 20 observations on the following 4 variables.

Study

Factor indicating the study from which data was taken

Lactate

Whether women had breast–fed children (lactated)

Cancer

Number of women with breast cancer

NoCancer

Number of women without breast cancer

Details

Meta–analysis refers to the analysis of analyses. When the main results of studies can be cast into 2\times2 tables of counts, it is natural to combine individual odds ratios with a logistic regression model that includes a factor to account for different odds from the different studies. In addition, the odds ratio itself might differ slightly among studies because of different effects on different populations or different research techniques. One approach for dealing with this is to suppose an underlying common odds ratio and to model between–study variability as extra–binomial variation.

Source

Ramsey, F.L. and Schafer, D.W. (2002). The Statistical Sleuth: A Course in Methods of Data Analysis (2nd ed), Duxbury.

References

Data gathered from various sources by Karolyn Kolassa as part of a Master's project, Oregon State University.

Examples

str(ex2119)

Sleuth2 documentation built on Jan. 25, 2024, 3:02 p.m.