inst/Examples/Readme.md

author: Kevin R. Coombes and Min Wang title: Code used for analyses in Thresher manuscript date: 2017-12-08

Overview

This folder contains the R code used to perform simulation and to analyze breast cancer data sets in our paper titled Thresher: Determining the Number of Clusters while Removing Outliers and published in ther jouirnal BMC Bioinformatics.

ExistingMethods

This subfolder contains scripts (and not packages) needed to implement the existing methods we use for comparison. In particular, we needed to make minor changes to the main NbClust driver function, since the version in the package rather impolitely overwrites the seed for the random number generator, thus breaking our simulation code.

Simulations

This subfolder contains the code that performs the simulations described in Section 3 of the manuscript.

BRCA

This subfoilder contains the code to analyze GEO breast cancer data sets, as described in Section 4 of the manuscript.



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Thresher documentation built on Dec. 8, 2019, 3:01 a.m.