Likelihood per locus of the observed alleles in a DNA mixture conditional on the number of contributors to the mixture
lik.loc function computes the likelihood of the observed data in a forensic DNA mixture, for each of the loci involved, conditional on the number of contributors to
the number of contributors to the DNA mixture
a factor giving the reference population in
a float from [0,1[ giving Wright's Fst coefficien.
the loci for which the likelihood shall be computed. Default (set to NULL) corresponds to all loci.
lik.loc computes the likelihood per locus of the observed alleles.
This function implements the general formula for the interpretation
of DNA mixtures in case of subdivided populations (Curran et al, 1999), in the particular case where all contributors
are unknown and belong to the same subpopulation.
The Fst coefficient given in the
theta argument allows accounting for population subdivision when all
contributors belong to the same subpopulation.
lik.loc returns a vector, of length the number of loci in
giving the likelihood of the data for each locus.
Hinda Haned <email@example.com>
Haned H, Pene L, Lobry JR, Dufour AB, Pontier D.
Estimating the number of contributors to forensic DNA mixtures: Does maximum likelihood
perform better than maximum allele count? J Forensic Sci, accepted 2010.
Curran JM, Triggs CM, Buckleton J, Weir BS. Interpreting DNA Mixtures in Structured Populations. J Forensic Sci 1999;44(5): 987-995
lik for the overall loci likelihood,
likestim.loc for the estimation of the number of contributors to a DNA mixture through
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data(strusa) #simulation of 1000 genotypes from the Caucasian allele frequencies gen<-simugeno(strusa,n=c(0,100,0)) #4-person mixture mix4 <- simumix(gen,ncontri=c(0,4,0)) lik.loc(x=2,mix4, strusa, refpop="Cauc") lik.loc(x=2,mix4, strusa, refpop="Afri") #You may also want to try: #likestim(mix4,strusa,refpop="Cauc")
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