Information-cost functions | R Documentation |
Functions to calculate information cost-ratios.
info2cost(sel.frac,cost,d,G=NULL,cross)
info2cost.bc(sel.frac,cost,d,G=NULL)
info2cost.f2(sel.frac,cost,d,G=NULL)
sel.frac |
Selection fraction; proportion of individuals genotyped |
cost |
Genotyping cost in units of raising an individual. When
|
d |
Marker spacing in centiMorgans |
G |
Genome size in Morgans |
cross |
Cross type, "bc"or "f2" |
The information calculations are done under the null hypothesis of no QTL effect.
For d!=0
it calculates the ratio of information in the
middle of a marker interval of length d
cM to the cost of
genotyping the cross. For d=0
, it calculates the ratio of
information at any locus to the cost of genotyping the cross.
Saunak Sen, Jaya Satagopan, Karl Broman, and Gary Churchill
Sen S, Satagopan JM, Churchill GA (2005) Quantitative trait locus study design from an information perspective. Genetics, 170:447-64.
info
info2cost(0.5,1,cross="bc")
info2cost(0.5,1,10,1450,cross="bc")
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