CHETAH (CHaracterization of cEll Types Aided by Hierarchical classification) is an accurate, selective and fast scRNA-seq classifier. Classification is guided by a reference dataset, preferentially also a scRNA-seq dataset. By hierarchical clustering of the reference data, CHETAH creates a classification tree that enables a step-wise, top-to-bottom classification. Using a novel stopping rule, CHETAH classifies the input cells to the cell types of the references and to "intermediate types": more general classifications that ended in an intermediate node of the tree.
Package details |
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Author | Jurrian de Kanter [aut, cre], Philip Lijnzaad [aut] |
Bioconductor views | Classification Clustering RNASeq SingleCell |
Maintainer | Jurrian de Kanter <jurriandekanter@gmail.com> |
License | file LICENSE |
Version | 1.6.0 |
URL | https://github.com/jdekanter/CHETAH |
Package repository | View on Bioconductor |
Installation |
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