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Strand specific peak-pair calling in ChIP-exo replicates. The cumulative Skellam distribution function (package 'skellam') is used to detect significant normalised count differences of opposed sign at each DNA strand (peak-pairs). Irreproducible discovery rate (IDR) for overlapping peak-pairs across biological replicates is estimated using the package 'idr'.
Package details |
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Author | Pedro Madrigal <bioinformatics.engineer@gmail.com> |
Bioconductor views | Genetics Sequencing Transcription |
Maintainer | Pedro Madrigal <bioinformatics.engineer@gmail.com> |
License | Artistic-2.0 | GPL-2 + file LICENSE |
Version | 1.28.0 |
Package repository | View on Bioconductor |
Installation |
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