simes_pval: Calculate region-level p-value
In DAMEfinder: Finds DAMEs - Differential Allelicly MEthylated regions
Description
Usage
Arguments
Details
Value
Description
This function uses the Simes method to calculate a regional-level p-value
based on the single-eBayes p-values. It highly depends on the choice of
maxGap in find_dames.
Usage
1
simes_pval(sat, smtstat, midpt)
Arguments
sat
Output from get_tstats.
smtstat
(Smoothed) tstat vector from get_tstats.
midpt
Coordinate vector for each CpG site/tuple.
Details
When used as a FDR-control method, for positively correlated P-values, Simes
method is even closer to the nominal alpha level than the Bonferroni-Holm
method.
Value
Vector of summarized pvals
DAMEfinder documentation built on Nov. 8, 2020, 11:10 p.m.
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Description Usage Arguments Details Value
Description
This function uses the Simes method to calculate a regional-level p-value
based on the single-eBayes p-values. It highly depends on the choice of
maxGap in find_dames.
Usage
1 | simes_pval(sat, smtstat, midpt)
|
Arguments
sat |
Output from |
smtstat |
(Smoothed) tstat vector from |
midpt |
Coordinate vector for each CpG site/tuple. |
Details
When used as a FDR-control method, for positively correlated P-values, Simes method is even closer to the nominal alpha level than the Bonferroni-Holm method.
Value
Vector of summarized pvals
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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