calculate_boundary: calculate_boundary

In DominoEffect: Identification and Annotation of Protein Hotspot Residues

Description

The function calculates boundaries of sequence windows around the mutation. It is possible to define up to two window lengths. If the mutation is close to the start or end of the protein, the region is extended into the other direction to keep the indicated size

Usage

calculate_boundary(mut_pos_numeric, length_aa, flanking_region)

Arguments

mut_pos_numeric	Amino acid position of mutation
length_aa	Length of transcript in amino acids
flanking_region	Vector containing two flanking regions

Value

returns a list with the boundaries for the two regions

Author(s)

Marija Buljan <[e-mail]> Peter Blattmann <[e-mail]>

Examples

calculate_boundary(250, 500, c(200, 300))
calculate_boundary(250, 500, 300)

DominoEffect documentation built on Nov. 8, 2020, 5:46 p.m.