getPatientOutlierMatrix: Compute the patient outlier matrix

In DriverNet: Drivernet: uncovering somatic driver mutations modulating transcriptional networks in cancer

Description

Given a real-value patient expression matrix, compute the patient outlier matrix and remove the genes which are not expressed.

Usage

getPatientOutlierMatrix(patExpMatrix, th=2)

Arguments

patExpMatrix	Patient Expression Matrix
th	The threshold, the default value is 2 ( the gene expression values outside the 2 standard deviation range are considered as outliers).

Value

The output patOutMatrix is an input to the computeDrivers method

Author(s)

Ali Bashashati, Reza Haffari, Jiarui Ding, Gavin Ha, Kenneth Liu, Jamie Rosner and Sohrab Shah

Maintainer: Jiarui Ding <[e-mail]>

See Also

computeDrivers

Examples

data(samplePatientExpressionMatrix)
samplePatientOutlierMatrix = getPatientOutlierMatrix(samplePatientExpressionMatrix)

DriverNet documentation built on Nov. 8, 2020, 10:59 p.m.