FilterFFPE: FFPE Artificial Chimeric Read Filter for NGS data

This package finds and filters artificial chimeric reads specifically generated in next-generation sequencing (NGS) process of formalin-fixed paraffin-embedded (FFPE) tissues. These artificial chimeric reads can lead to a large number of false positive structural variation (SV) calls. The required input is an indexed BAM file of a FFPE sample.

Package details

AuthorLanying Wei [aut, cre] (<https://orcid.org/0000-0002-4281-8017>)
Bioconductor views Alignment Preprocessing QualityControl Sequencing StructuralVariation
MaintainerLanying Wei <lanying.wei@uni-muenster.de>
LicenseLGPL-3
Version1.0.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("FilterFFPE")

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FilterFFPE documentation built on Nov. 8, 2020, 8:10 p.m.