heart.metaXcan: heart.metaXcan

Description Usage Format Source

Description

The MetaXcan-predicted differential gene expression from the cardiovascular disease (CVD) GWAS, CARDIoGRAMplusC4D (60,801 cases, 123,504 controls and 9.4M SNPs).

Usage

1

Format

A data frame with the following items:

gene

a gene's id

gene_name

a gene's name

zscore

MetaXcan's association result for the gene

effect_size

MetaXcan's association effect size for the gene

pvalue

P-value of the aforementioned statistic

pred_perf_r2

R2 of transcriptome prediction model's correlation to gene's measured transcriptome

pred_perf_pval

pval of transcriptome prediction model's correlation to gene's measured transcriptome

pred_perf_qval

qval of transcriptome prediction model's correlation to gene's measured transcriptome

n_snps_used

number of snps from GWAS that got used in MetaXcan analysis

n_snps_in_cov

number of snps in the covariance matrix

n_snps_in_model

number of snps in the prediction model

var_g

variance of the gene expression

...

Source

http://www.cardiogramplusc4d.org/data-downloads/;https://cloud.hakyimlab.org/s-predixcan


GIGSEA documentation built on Nov. 8, 2020, 7:02 p.m.