Function to apply lowess normalization to an expression set.

Description

Like lnorm, but applies to and returns an ExpressionSet or AffyBatch object instead of a matrix.

Usage

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lnormeS(eS, span=0.1)

Arguments

eS

An ExpressionSet or AffyBatch object

span

Smoothing parameter for lowess. Larger values correspond to more smoothness.

Value

Returns an ExpressionSet with exprs(eS) normalized by lnorm.

Author(s)

John Tillinghast, Blythe Durbin-Johnson

References

http://dmrocke.ucdavis.edu

See Also

lnorm, norm

Examples

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library(LMGene)
library(Biobase)

data(sample.eS)

# glog transform expression set
trsample.eS <- transeS (sample.eS, 667, 65)

# normalize expression set
normtrsample.eS <- lnormeS (trsample.eS)