Description Usage Arguments Value Author(s) References See Also Examples

Finds inter-quartile range of the data = {75th percentile - 25th percentile}.

1 | ```
iqr(x)
``` |

`x` |
x is a vector for which IQR has to be found. |

Returns a numeric value representing the difference of 75th percentile and 25th percentile of the vector. It is used for normalization across the chips - basic assumption is that net differential expression of the middle half of the genes in microarray experiment is zero, which is conservative assumption as typically only 5-10 differential expression.

Nitin Jain[email protected]

J.K. Lee and M.O.Connell(2003). *An S-Plus library for the analysis of differential expression*. In The Analysis of Gene Expression Data: Methods and Software. Edited by G. Parmigiani, ES Garrett, RA Irizarry ad SL Zegar. Springer, NewYork.

Jain et. al. (2003) *Local pooled error test for identifying
differentially expressed genes with a small number of replicated microarrays*, Bioinformatics, 1945-1951.

Jain et. al. (2005) *Rank-invariant resampling based estimation of false discovery rate for analysis of small sample microarray data*, BMC Bioinformatics, Vol 6, 187.

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LPE documentation built on Nov. 17, 2017, 8:24 a.m.

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