ssea.analyze.statistic: MSEA statistics for enrichment score

Description Usage Arguments Value Author(s) References See Also Examples

View source: R/cle.LS.R

Description

ssea.analyze.statistic estimates the enrichment score based on observed and expected ones.

Usage

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Arguments

o

observed enrichment score

e

expected enrichment score

Value

score

estimated enrichment score based on observed and expected scores

Author(s)

Ville-Petteri Makinen

References

Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Makinen V-P, Yang X. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems. BMC genomics. 2016;17(1):874.

See Also

ssea.analyze

Examples

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## O and E the observed and expected counts of positive findings 
## (enrichment scores) at a given cutoff:
set.seed(1)
o <- rnorm(1)
e <- rnorm(1)
## find the final enrichment score from the observed and estimated scores:
z <- ssea.analyze.statistic(o, e)

Mergeomics documentation built on Nov. 8, 2020, 6:58 p.m.