ssea.analyze.statistic: MSEA statistics for enrichment score
In Mergeomics: Integrative network analysis of omics data

Description Usage Arguments Value Author(s) References See Also Examples

ssea.analyze.statistic estimates the enrichment score based on observed and expected ones.

1	ssea.analyze.statistic(o, e)

`o`	observed enrichment score
`e`	expected enrichment score

score

estimated enrichment score based on observed and expected scores

Ville-Petteri Makinen

Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Makinen V-P, Yang X. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems. BMC genomics. 2016;17(1):874.

ssea.analyze

## O and E the observed and expected counts of positive findings 
## (enrichment scores) at a given cutoff:
set.seed(1)
o <- rnorm(1)
e <- rnorm(1)
## find the final enrichment score from the observed and estimated scores:
z <- ssea.analyze.statistic(o, e)