wgcna.one.step: Module identification

Description Usage Arguments Details Value References See Also Examples

View source: R/wgcna.one.step.R

Description

This function is a wrapper function for blockwiseModules and passes its arguments to it. Some other arguments are fixed.

Usage

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wgcna.one.step(Data, power, saveDir=".", blockSize = "All", saveTOMs = FALSE, 
   doThreads=FALSE, verbose = 0, seed = NULL)

Arguments

Data

A matrix or data frame containing the expression data, with genes corresponding to columns and rows corresponding to samples. Rows and columns must be named.

power

Soft-thresholding power for network construction

saveDir

The directory to save the results and plots. NULL will disable saving.

blockSize

The size of block when the data is too big. If not "All" (default) may introduce artifacts.

saveTOMs

Boolean determining if the TOM data should be saved, which can be hundreds of MBs and useful for identifying hubs.

doThreads

Boolean. Allows WGCNA to run a little faster using multi-threading but might not work on all systems.

verbose

The integer level of verbosity. 0 means silent and higher values produce more details of computation.

seed

Random seed to ensure reproducibility.

Details

Data, power, blockSize, saveTOMs, verbose, and seed are passd to blockwiseModules.

Value

A list with following components

call

The command that created the results

genes

The names of Data columns

modules

A numeric vector, named by genes, that reports the module (clustering) assignments.

moduleColors

A character vector, named by genes, that reports the color of each gene according to its module assignment

net

The full output of blockwiseModules function

netFile

The file in which the net object is saved

power

An echo of the power argument.

References

Langfelder P and Horvath S, WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics 2008, 9:559

See Also

blockwiseModules, pickSoftThreshold, calculate.beta

Examples

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     data(aml)
     data(mds)
     wgRes <- wgcna.one.step(Data=aml[,1:200], seed=1, power=7,
                                 saveDir="wgcna", verbose=1)

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