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##' @title Interactive MultiAssayExperiment Explorer
##'
##' @description
##'
##' A shiny app to browser and explore the assays in an
##' `MultiAssayExperiment` object. Each assay can be selected from the
##' dropdown meny in the side panel, and the quantitative data and row
##' metadata are displayed in the respective *Assay* and *Row data*
##' tabs. The *Heatmap* tab displays a heatmap of the assay. The
##' selection of rows in the *Row data* table is used to subset the
##' features displayed in the *Assay* table and the heatmap to those
##' currectly selected. See [QFeatures] for an example.
##'
##' @param object An instance inheriting from `MultiAssayExperiment`.
##'
##' @param n A `numeric(1)` indicating the maximum number of features
##' (rows) to consider before disabling row clustering and
##' displaying feature names for speed purposes. Default is 100.
##'
##' @param ... Additional parameters (other than `Rowv` and `labRow`,
##' which are set internally based on the value of `n`) passed to
##' heatmap.
##'
##' @return Used for its side effect.
##'
##' @md
##'
##' @author Laurent Gatto
##'
##' @importFrom stats heatmap
##'
##' @export
##'
##' @examples
##' \dontrun{
##' data(feat2)
##' display(feat2)
##' }
display <- function(object, n = 100, ...) {
stopifnot(inherits(object, "MultiAssayExperiment"))
requireNamespace("DT")
requireNamespace("shiny")
requireNamespace("shinydashboard")
ui <- shinydashboard::dashboardPage(
shinydashboard::dashboardHeader(title = "MultiAssayExperiment Viewer"),
shinydashboard::dashboardSidebar(
shiny::actionButton("clear_rows", "Clear row selection"),
shiny::selectInput("name", "Assay:", names(object))
),
shinydashboard::dashboardBody(
shinydashboard::tabBox(
width = 12,
shiny::tabPanel(title = "Heatmap",
shiny::plotOutput("heatmap")),
shiny::tabPanel(title = "Assay",
DT::dataTableOutput("assay")),
shiny::tabPanel(title = "Row data",
DT::dataTableOutput("rowdata"))
)
)
)
server <- function(input, output) {
shiny::observeEvent(input$clear_rows, {
DT::selectRows(proxy_rowdata, NULL)
})
output$heatmap <- shiny::renderPlot({
.Rowv <- NULL
.labRow <- NULL
.assay <- assay(object[[input$name]])
sel <- input$rowdata_rows_selected
if (!length(sel)) sel <- TRUE
if ((is.logical(sel) & sel) || (length(sel) > n)) {
.Rowv <- NA
.labRow <- NA
}
heatmap(.assay[sel, , drop = FALSE],
Rowv = .Rowv, labRow = .labRow, ...)
})
output$assay <- DT::renderDataTable({
.assay <- assay(object[[input$name]])
sel <- input$rowdata_rows_selected
if (!length(sel)) sel <- TRUE
data.frame(.assay[sel, , drop = FALSE])
})
output$rowdata <- DT::renderDataTable({
.rowdata <- rowData(object[[input$name]])
data.frame(.rowdata)
}, selection = list(target = 'row'))
proxy_rowdata <- DT::dataTableProxy('rowdata')
}
shiny::shinyApp(ui, server)
}
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