cmap: Data from Connectivity map build 01

In RGSEA: Random Gene Set Enrichment Analysis

Description

It is the sample data used for testing the function RGSEAsd.

Usage

data(cmap)

Format

The format is: num [1:22268, 1:6] 0.4892 -0.6137 3.5242 -0.0139 -2.0255 ... - attr(*, "dimnames")=List of 2 ..$ : chr [1:22268] "1007_s_at" "1053_at" "117_at" "121_at" ... ..$ : chr [1:6] "thioridazine" "tretinoin" "prochlorperazine" "chlorpromazine" ...

Details

The query data is the instance 5202764005791175120104.C08, treated with thioridazine.

The reference data is 5202764005789148112904.G05, X5202764005789148112904.F03, X5202764005789148112904.F05, X5202764005789148112904.E02, X5202764005789148112904.E04. They were treated with tretinoin, prochlorperazine, chlorpromazine, vorinostat, sirolimus respectively. All the data were generated by MCF7 cell line.

Source

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5258

References

Lamb J, Crawford ED, Peck D, Modell JW et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 2006 Sep 29;313(5795):1929-35. PMID: 17008526

Examples

data(cmap)

Example output

RGSEA documentation built on Nov. 8, 2020, 8:25 p.m.