This is an internal fitting of the group regression. For a single combination of possible tau and d values the group regression is fist fit, then predicted values are obtained and regressed against the original sequencing depths. The estimates slope is passed back to the SCnorm_fit() function.
specifies a column of the grid matrix of tau and d.
contains the expression values, sequencing depths to fit the group regression, and the quantile used in the individual gene regression for grouping.
estimated count-depth relationship of predicted values for one value of tau and degree.
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