Estimation of proportion of differentially expressed genes. This estimation is based on a histogram of the p-values. More specifically, based on the horizontal line representing a uniform distribution based on the p value distribution between 0.5 and 1. This represents the hypothetical p value distribution arising just by chance. All genes with small p-values above this line reflect the expected number of differentially expressed genes not by chance.
a vector of p-values
Willem Talloen and Tobias Verbeke
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