hotspotFinder: hotspotFinder
In iBMQ: integrated Bayesian Modeling of eQTL data

Description Usage Arguments Value Examples

One main advantage of our method is its increased sensitivity for finding trans-eQTL hotspots (corresponding to situations where a single SNP is linked to the expression of several genes across the genome).

1	hotspotFinder(peak, numgene)

`peak`	A data frame (3 columns) corresponding to the output of the eqtlFinder function or the data frame (9 columns) corresponding to the output of the eqtlClassifier function.
`numgene`	The minimum of gene to detect.

The output of this function is a list, where each element is a marker. For each marker there is a data frame with all the eQTLs linked to this marker.

data(PPA.liver)
cutoff.liver <- calculateThreshold(PPA.liver, 0.2)
eqtl.liver <- eqtlFinder(PPA.liver, cutoff.liver)
hotspot.liver <- hotspotFinder(eqtl.liver,20)