module_miRtarget: module_miRtarget

In miRSM: Inferring miRNA sponge modules in heterogeneous data

Description

Extract miRNA-target interactions of each miRNA sponge module

Usage

module_miRtarget(share_miRs, Modulelist)

Arguments

share_miRs	List object: a list of common miRNAs of each miRNA sponge module generated by share_miRs function.
Modulelist	List object: a list of the identified miRNA sponge modules.

Value

List object: miRNA-target interactions of each miRNA sponge module.

Author(s)

Junpeng Zhang (https://www.researchgate.net/profile/Junpeng_Zhang3)

Examples

data(BRCASampleData)
modulegenes_WGCNA <- module_WGCNA(ceRExp, mRExp)
# Identify miRNA sponge modules using sensitivity RV coefficient (SRVC)
miRSM_WGCNA_SRVC <- miRSM(miRExp, ceRExp, mRExp, miRTarget,
                        modulegenes_WGCNA, method = "SRVC",
                        SMC.cutoff = 0.01, RV_method = "RV")
miRSM_WGCNA_SRVC_genes <- miRSM_WGCNA_SRVC[[2]]
miRSM_WGCNA_share_miRs <-  share_miRs(miRExp, ceRExp, mRExp, 
                                      miRTarget, miRSM_WGCNA_SRVC_genes)
miRSM_WGCNA_miRtarget <- module_miRtarget(miRSM_WGCNA_share_miRs, 
                                          miRSM_WGCNA_SRVC_genes)

miRSM documentation built on April 16, 2021, 6 p.m.