Description Usage Arguments Details Value Author(s) References

View source: R/rma.background.correct.R

Background correct each column of a matrix

1 |

`x` |
A matrix of intensities where each column corresponds to a chip and each row is a probe. |

`copy` |
Make a copy of matrix before background correctiong. Usually safer to work with a copy, but in certain situations not making a copy of the matrix, but instead background correcting it in place will be more memory friendly. |

Assumes PMs are a convolution of normal and exponentional. So we
observe X+Y where X is backround and Y is signal. `bg.adjust`

returns E[Y|X+Y, Y>0] as our backround corrected
PM.

A RMA background corrected `matrix`

.

Ben Bolstad, bmbolstad.com

Bolstad, BM (2004) *Low Level Analysis of High-density
Oligonucleotide Array Data: Background, Normalization and
Summarization*. PhD Dissertation. University of California,
Berkeley. pp 17-21

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