neg_loglikelihood_chunk: Calculate negative penalized likelihood, used for calls to...

In scBFA: A dimensionality reduction tool using gene detection pattern to mitigate noisy expression profile of scRNA-seq

Description

The penalized likelihood function: f(A,Z,β,O,U) = ∑ [lnP(B;A,Z,U,V,β,γ)]_ij - ε_1 * ||A||_2^2 - ε_2 * ||Z||_2^2 - ε_3*||β||_2^2 - ε_2 * ||γ||_2^2

Usage

neg_loglikelihood_chunk(parameters, modelEnv)

Arguments

parameters	Vectorized parameter space.
modelEnv	Environment variable contains parameter space, and global variables such as N,G,C,detection matrix B, etc

Value

Scalar penalized likelihood

scBFA documentation built on Nov. 8, 2020, 5:24 p.m.