bootstrap_parallel: BootStrap runs for both scGPS training and prediction with...

In scGPS: A complete analysis of single cell subpopulations, from identifying subpopulations to analysing their relationship (scGPS = single cell Global Predictions of Subpopulation)

Description

same as bootstrap_prediction, but with an multicore option

Usage

bootstrap_parallel(ncores = 4, nboots = 1, genes = genes,
  mixedpop1 = mixedpop1, mixedpop2 = mixedpop2, c_selectID,
  listData = list(), cluster_mixedpop1 = NULL,
  cluster_mixedpop2 = NULL)

Arguments

ncores	a number specifying how many cpus to be used for running
nboots	a number specifying how many bootstraps to be run
genes	a gene list to build the model
mixedpop1	a SingleCellExperiment object from a mixed population for training
mixedpop2	a SingleCellExperiment object from a target mixed population for prediction
c_selectID	the root cluster in mixedpop1 to becompared to clusters in mixedpop2
listData	a list object, which contains trained results for the first mixed population
cluster_mixedpop1	a vector of cluster assignment for mixedpop1
cluster_mixedpop2	a vector of cluster assignment for mixedpop2

Value

a list with prediction results written in to the index out_idx

Author(s)

Quan Nguyen, 2017-11-25

Examples

day2 <- day_2_cardio_cell_sample
mixedpop1 <-new_scGPS_object(ExpressionMatrix = day2$dat2_counts, 
    GeneMetadata = day2$dat2geneInfo, CellMetadata = day2$dat2_clusters)
day5 <- day_5_cardio_cell_sample
mixedpop2 <-new_scGPS_object(ExpressionMatrix = day5$dat5_counts, 
    GeneMetadata = day5$dat5geneInfo, CellMetadata = day5$dat5_clusters)
genes <-training_gene_sample
genes <-genes$Merged_unique
#prl_boots <- bootstrap_parallel(ncores = 4, nboots = 1, genes=genes,
#    mixedpop1 = mixedpop2, mixedpop2 = mixedpop2,  c_selectID=1,
#    listData =list())
#prl_boots[[1]]$ElasticNetPredict
#prl_boots[[1]]$LDAPredict

scGPS documentation built on Nov. 8, 2020, 5:22 p.m.