filterCV-methods: Coefficient of variation filter

In viper: Virtual Inference of Protein-activity by Enriched Regulon analysis

Description

This function filter redundant probes based on the highest coefficient of variation

Usage

filterCV(expset, ...)

## S4 method for signature 'matrix'
filterCV(expset)

## S4 method for signature 'ExpressionSet'
filterCV(expset)

Arguments

expset	Expression set or Matrix containing the gene expression data, with samples in columns and probes in rows. The colnames attribute should contain the sample names and the rownames attribute should contain the unique geneIDs
...	Additional parameters added to keep compatibility

Value

CV filtered dataset

Examples

data(bcellViper, package="bcellViper")
d1 <- exprs(dset)
tmp <- rownames(d1)
tmp[round(runif(10, 1, length(tmp)))] <- tmp[1]
rownames(d1) <- tmp
dim(d1)
d1 <- filterCV(d1)
dim(d1)

viper documentation built on Nov. 8, 2020, 7:37 p.m.