msviperClass: msVIPER class

In viper: Virtual Inference of Protein-activity by Enriched Regulon analysis

Description

This function generates an instance of the msviper class from a signature, NES signature and regulon object

Usage

msviperClass(nes, signature, regulon, nullmodel = NULL)

Arguments

nes	Numeric vector of NES values
signature	Numeric vector of gene expression signature
regulon	Instance of class regulon
nullmodel	Optional matrix containing the signatures for the null model

Value

msviper class object

Examples

data(bcellViper, package="bcellViper")
sig <- rowTtest(dset, "description", c("CB", "CC"), "N")$statistic
mra <- msviper(sig, regulon)
mra1 <- msviperClass(mra$es$nes, sig, regulon)
summary(mra1)
plot(mra1)

viper documentation built on Nov. 8, 2020, 7:37 p.m.