vulcan: VirtUaL ChIP-Seq data Analysis using Networks
Version 1.0.0

Vulcan (VirtUaL ChIP-Seq Analysis through Networks) is a package that interrogates gene regulatory networks to infer cofactors significantly enriched in a differential binding signature coming from ChIP-Seq data. In order to do so, our package combines strategies from different BioConductor packages: DESeq for data normalization, ChIPpeakAnno and DiffBind for annotation and definition of ChIP-Seq genomic peaks, csaw to define optimal peak width and viper for applying a regulatory network over a differential binding signature.

Package details

AuthorFederico M. Giorgi, Andrew N. Holding, Florian Markowetz
Bioconductor views ChIPSeq GeneExpression NetworkEnrichment SystemsBiology
MaintainerFederico M. Giorgi <[email protected]>
LicenseLGPL-3
Version1.0.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
source("https://bioconductor.org/biocLite.R")
biocLite("vulcan")

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vulcan documentation built on Nov. 17, 2017, 1:39 p.m.