aldex.mem.sim: Simulation for testing mixed effects models.
In ALDEx3: Linear Models for Sequence Count Data

aldex.mem.sim

R Documentation

Simulation for testing mixed effects models.

Includes random intercpt, option to include random slope, second random intercept, and time-correlation.

aldex.mem.sim(
  D,
  days,
  subjects,
  depth = 10000,
  location = 1,
  random_slope = FALSE,
  corr = 0,
  rho_ar1 = 0,
  sd_resid = 0.1
)

`D`	number of taxa/genes
`days`	num days (i.e., repeated measurements) for each subject
`subjects`	num of subjects to simulate
`depth`	sum of counts for each multinomial draw
`location`	second random intercept, if 0 ignore, else simulate num of locations
`random_slope`	If true, simulate a random slope for each subject.
`corr`	The correlation between slope/random intercept
`rho_ar1`	The ar1 time-correlation, if 0, don't simulate
`sd_resid`	The residual error time-correlation.