ASP.Score: Score test of association

In ASPBay: Bayesian Inference on Causal Genetic Variants using Affected Sib-Pairs Data

Description

Calculate score statistics and the associated P-value for each SNPs

Usage

 ASP.Score(Tem_Gen, Index_Gen, IBD) 

Arguments

Tem_Gen	Genotypes of controls (denoted by the number of alternative allele)
Index_Gen	Genotypes of Index cases
IBD	IBD states for each affected sib pair

Details

Give the values of statistic and p-value of the association score test.

Value

List of 2 vectors of length the number of SNPs:

Value	Statistic values for each SNPs
Pvalue	P-values of the score test for each SNPs

Author(s)

Claire Dandine-Roulland

References

Perdry, Herve, Muller-Myhsok, Bertram, et Clerget-Darpoux, Francoise. Using affected sib-pairs to uncover rare disease variants. Hum Hered, 2013.

See Also

ASP.Selection

Examples

data(ASPData)
ASP.Score(ASPData$Control, ASPData$Index, ASPData$IBD )

ASPBay documentation built on May 2, 2019, 8:55 a.m.