Description Usage Arguments Details Value Author(s) References See Also Examples
View source: R/ASP.Selection.R
Select a subset of SNPs using discrimination method for affected sib pairs
1 | ASP.Selection(Tem_Gen, Index_Gen, IBD, k = log(10000))
|
Tem_Gen |
Genotypes of controls (denoted by the number of alternative allele) |
Index_Gen |
Genotypes of index cases |
IBD |
IBD states for each affected sib pair |
k |
Selection threshold (by default log(1e4)) |
Take the genotypes of controls and index cases and the IBD states. Give the score statistics, discrimination statistics and the subset of selected SNPs with the chosen threshold.
List of 4 vectors with components:
score |
The values of the score statistic for each SNPs |
stat |
The values of discrimination statistic comparing each SNPs with the most associated SNP |
SNP_subset |
The indexes (numbers of columns) of selected SNPs |
SNPname_subset |
The names (names of columns) of selected SNPs |
Claire Dandine-Roulland
Dandine-Roulland, Claire and Perdry, Herve. Where is the causal variant? On the advantage of the family design over the case-control design in genetic association studies. Submitted to Eur J Hum Genet
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