dot-get_signf_results: Returns significant results

In ActiveDriverWGS: A Driver Discovery Tool for Cancer Whole Genomes

Returns significant results

Description

Returns significant results

Usage

.get_signf_results(all_res)

Arguments

all_res

a data frame containing the following columns id A string identifying the element of interest pp_element The p-value of the element element_muts_obs The number of patients with a mutation in the element element_muts_exp The expected number of patients with a mutation in the element with respect to background element_enriched A boolean indicating whether the element is enriched in mutations pp_site The p-value of the element site_muts_obs The number of patients with a mutation in the site site_muts_exp The expected number of patients with a mutation in the site with respect to element site_enriched A boolean indicating whether the site is enriched in mutations result_number A numeric indicator denoting the order in which the results were calculated

Value

the same data frame with three addition columns

fdr_element

The FDR corrected p-value of the element

fdr_site

The FDR corrected p-value of the site

has_site_mutations

A V indicates the presence of site mutations

ActiveDriverWGS documentation built on Sept. 3, 2022, 5:05 p.m.