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It has been designed to calculate the required sample size in randomized clinical trials with composite endpoints. This package also includes functions to calculate the probability of observing the composite endpoint and the expected effect on the composite endpoint, among others. The methods implemented can be found in Bofill & Gómez (2019) <doi:10.1002/sim.8092> and Gómez & Lagakos (2013) <doi:10.1002/sim.5547>.
Package details 


Author  Marta Bofill Roig [aut, cre], Jordi Cortes Martinez [aut], Guadalupe Gomez Melis [ctb] 
Maintainer  Marta Bofill Roig <marta.bofill.roig@upc.edu> 
License  GPL3 
Version  1.7 
Package repository  View on CRAN 
Installation 
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