simdurbin: Gene intensities simulator

simdurbinR Documentation

Gene intensities simulator

Description

Simulates gene intensities from the two components model as in the papers of Durbin and Rocke.

Usage

simdurbin(n, alpha, mu, seta, seps)

Arguments

n

number of intensities to be simulated

alpha

background mean of gene intensities

mu

the means where the gene intensities are simulated from

seta

standard deviation of high-level gene intensities

seps

standard deviation of low-level gene intensities

Details

This function generates n intensities from the Durbin and Rocke (2001) gene intensity model with parameters alpha, seta and seps.

Value

A vector of the appropriate intensities.

Author(s)

Guy Nason <g.p.nason@bris.ac.uk>

References

Rocke, D.M. and Durbin, B.P. (2001), A model for measurement error for gene expression arrays, Journal of Computational Biology, 8, 557-569

See Also

simdurbin2


DDHFm documentation built on Oct. 4, 2024, 5:11 p.m.