Description Usage Arguments Value Author(s) References See Also Examples
Simulates gene intensities from the two components model of Durbin and Rocke.
1 | simdurbin2(mu, alpha, seta, seps)
|
mu |
the means where the gene intensities are simulated from |
alpha |
background mean of gene intensities |
seta |
standard deviation of high-level gene intensities |
seps |
standard deviation of low-level gene intensities |
Like simdurbin
this function simulates gene
intensities from the Durbin and Rocke two component model (see
Durbin and Rocke, 2001). Unlike simdurbin
this function
generates each intensity with a mean specified by an entry in
mu
. So, length(mu)
intensities are generated with
intensity i
having mean mu[i]
.
Guy Nason <g.p.nason@bris.ac.uk>
Rocke, D.M. and Durbin, B.P. (2001), A model for measurement error for gene expression arrays, Journal of Computational Biology, 8, 557-569
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