DIME: Differential Identification using Mixture Ensemble

A robust identification of differential binding sites method for analyzing ChIP-seq (Chromatin Immunoprecipitation Sequencing) comparing two samples that considers an ensemble of finite mixture models combined with a local false discovery rate (fdr) allowing for flexible modeling of data. Methods for Differential Identification using Mixture Ensemble (DIME) is described in: Taslim et al., (2011) <doi:10.1093/bioinformatics/btr165>.

Package details

AuthorCenny Taslim [aut, cre], Dustin Potter [ctb], Abbasali Khalili [ctb], Shili Lin [ctb]
MaintainerCenny Taslim <cenny.taslim@nationwidechildrens.org>
LicenseGPL (>= 2)
Version1.3.1
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("DIME")

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DIME documentation built on Sept. 27, 2026, 5:07 p.m.