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DoseFinding: Planning and Analyzing Dose Finding Experiments
The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology (Pinheiro et al. (2014) <doi:10.1002/sim.6052>).
Package details |
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| Author | Bjoern Bornkamp [aut] (<https://orcid.org/0000-0002-6294-8185>), Jose Pinheiro [aut], Frank Bretz [aut], Ludger Sandig [aut], Marius Thomas [aut, cre], Novartis Pharma AG [cph, fnd] |
| Maintainer | Marius Thomas <marius.thomas@novartis.com> |
| License | GPL-3 |
| Version | 1.2-1 |
| URL | https://github.com/openpharma/DoseFinding |
| Package repository | View on CRAN |
| Installation |
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