DoseFinding: Planning and Analyzing Dose Finding Experiments

The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology (Pinheiro et al. (2014) <doi:10.1002/sim.6052>).

Package details

AuthorBjoern Bornkamp [aut, cre] (<>), Jose Pinheiro [aut], Frank Bretz [aut], Ludger Sandig [aut]
MaintainerBjoern Bornkamp <>
Package repositoryView on CRAN
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DoseFinding documentation built on June 25, 2021, 5:07 p.m.