adipose: Gene Expression in Human White Adipose Tissue

In FunCluster: Functional Profiling of Microarray Expression Data

Description

This data set resulted from microarray experiments performed on human white adipose tissue after the separation of its two cellular components: mature adipocytes and stroma vascular fraction (SVF) cells, the non adipose component of the tissue. The purpose of this experimental model was to distinguish the two cellular fractions from a functional perspective and, in the meantime, to help establish the contribution of adipose and non adipose cells in the expression of inflammatory molecules in morbid obesity.

Usage

data(adipose)

Format

Three data frames containing significant genes specifically expressed in human mature adipocytes or in stroma vascular fraction cells of human white adipose tissue and a reference list with all the genes tested for differential expression during this experiment.

Source

http://corneliu.henegar.info/FunCluster.htm

References

Cancello R, Henegar C, Viguerie N, Taleb S, Poitou C, Rouault C, Coupaye M, Pelloux V, Hugol D, Bouillot JL, Bouloumie A, Barbatelli G, Cinti S, Svensson PA, Barsh GS, Zucker JD, Basdevant A, Langin D, Clement K. Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes 2005; 54(8):2277-86.

See Also

FunCluster, annotations.

FunCluster documentation built on May 2, 2019, 8:36 a.m.