Weight genes in pathways with a gene association network after correction for multi-subunit proteins

Description

Given a gene functional association network and a list of multi-subunit proteins, the gene weights in a list of pathways are assigned with a procedure of correction for multi-subunit proteins.

Usage

1
weight.gsets.with.msprot(gsets, isets.multi, msp.groups)

Arguments

gsets

A gene association network stored in a list.

isets.multi

Pathways stored in the form of a list of gene sets.

msp.groups

A list of multi-subunit proteins.

Value

A list of named numeric vectors storing gene weights, with gene names in the vector names.

Author(s)

Zhaoyuan Fang, Weidong Tian and Hongbin Ji

References

Zhaoyuan Fang, Weidong Tian and Hongbin Ji. A Network-Based Gene Weighting Approach for Pathway Analysis. Submitted.

See Also

weight.gsets.test