Description Usage Arguments Details Value Author(s) References See Also Examples
Armitage's trend test for the 2x3 genotype table.
1 | Armitage(case_11, case_12, case_22, control_11, control_12, control_22)
|
case_11 |
a non-negative integer, the frequency of genotype "allele1/allele1" in case samples. |
case_12 |
a non-negative integer, the frequency of genotype "allele1/allele2" in case samples. |
case_22 |
a non-negative integer, the frequency of genotype "allele2/allele2" in case samples. |
control_11 |
a non-negative integer, the frequency of genotype "allele1/allele1" in control samples. |
control_12 |
a non-negative integer, the frequency of genotype "allele1/allele2" in control samples. |
control_22 |
a non-negative integer, the frequency of genotype "allele2/allele2" in control samples. |
The Cochran-Armitage test for trend, is used in categorical data analysis when the aim is to assess for the presence of an association between a variable with two categories and a variable with k categories. It modifies the Pearson chi-squared test to incorporate a suspected ordering in the effects of the k categories of the second variable. The trend test is ofen used as a genotype-based test for case-control genetic association studies.
statistic |
numeric, the statistic of armitage test for trend. |
pValue |
numeric, the p value of armitage test for trend. |
Lanying Zhang and Yongshuai Jiang <jiangyongshuai@gmail.com>
Armitage, P(1955): Tests for Linear Trends in Proportions and Frequencies.
statgen.org(2007): A derivation for Armitage's trend test for the 2x3 genotype table.
OR
,
OR.TradPerm
,
OR.MCPerm
,
Armitage.TradPerm
,
Armitage.MCPerm
,
chisq.test
,
chisq.TradPerm
,
chisq.MCPerm
,
fisher.test
,
fisher.TradPerm
,
fisher.MCPerm
,
meta
,
meta.TradPerm
,
meta.MCPerm
,
permuteGenotype
,
rhyper
,
permuteGenotypeCount
,
genotypeStat
1 2 3 4 5 6 7 | # case_11=4
# case_12=1
# case_22=1
# control_11=3
# control_12=0
# control_22=0
# Armitage(case_11,case_12,case_22,control_11,control_12,control_22)
|
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