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MLML2R: Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions
Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2019) <doi:10.1515/sagmb-2018-0031>.
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Package details |
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| Author | Samara Kiihl [aut, cre], Maria Jose Martinez-Garrido [aut], Arce Domingo-Relloso [aut], Jose Bermudez [aut], Maria Tellez-Plaza [aut] |
| Bioconductor views | DNAMethylation Epigenetics MethylationArray Microarray OneChannel Software TwoChannel |
| Maintainer | Samara Kiihl <samara@ime.unicamp.br> |
| License | MIT + file LICENSE |
| Version | 0.3.3 |
| URL | https://github.com/samarafk/MLML2R |
| Package repository | View on CRAN |
| Installation |
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