MLML2R: Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions

Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2019) <doi:10.1515/sagmb-2018-0031>.

Package details

AuthorSamara Kiihl [aut, cre], Maria Jose Martinez-Garrido [aut], Arce Domingo-Relloso [aut], Jose Bermudez [aut], Maria Tellez-Plaza [aut]
Bioconductor views DNAMethylation Epigenetics MethylationArray Microarray OneChannel Software TwoChannel
MaintainerSamara Kiihl <>
LicenseMIT + file LICENSE
Package repositoryView on CRAN
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MLML2R documentation built on Oct. 30, 2019, 11:41 a.m.