MLML2R: Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions

Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2018, to appear).

Package details

AuthorSamara Kiihl [aut, cre], Maria Jose Martinez-Garrido [aut], Arce Domingo-Relloso [aut], Jose Bermudez [aut], Maria Tellez-Plaza [aut]
Bioconductor views DNAMethylation Epigenetics MethylationArray Microarray OneChannel Software TwoChannel
MaintainerSamara Kiihl <[email protected]>
LicenseMIT + file LICENSE
Version0.3.1
URL https://github.com/samarafk/MLML2R
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("MLML2R")

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MLML2R documentation built on Nov. 12, 2018, 5:03 p.m.