ADRand | R Documentation |
This function performs a simulation-based evaluation of operating characteristics for multi-stage adaptive Phase II trials that employ response-adaptive randomization. Patients are assigned to receive placebo or one of several doses of the experimental treatment. The efficacy data at the end of each stage are used to update the randomization scheme for the next stage with the ultimate goal of assigning most patients to the most effective doses. For an example of the function call, see ADRandExample.
ADRand(parameters)
parameters |
List of the trial design and other parameters. The required elements are defined below:
|
The function returns an object of class ‘ADRandResults’. This object is a list with the following components:
parameters |
List containing the user-specified parameters. |
sim_results |
List with multiple data frames containing key descriptive statistics for each simulation run. |
A detailed summary of the simulation results can be created using the GenerateReport
function.
ADRandApp
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