cvsim-class: The cvsim Class.

In MetabolicSurv: A Biomarker Validation Approach for Classification and Predicting Survival Using Metabolomics Signature

Description

The cvsim Class.

Slots

HRpca

A 3-way array in which first, second, and third dimensions correspond to number of metabolites, Hazard ratio infromation(Estimated HR, LowerCI and UpperCI), and number of cross validation respectively. This contains the estimated HR on test data and dimension reduction method is PCA.

HRpls

A 3-way array in which first, second, and third dimensions correspond to number of metabolites, Hazard ratio infromation(Estimated HR, LowerCI and UpperCI), and number of cross validation respectively. This contains the estimated HR on test data and dimension reduction method is PLS.

Nmets

The number of metabolites in the reduced matrix

Ncv

The number of cross validation done

Top

A sequence of top k metabolites considered. Default is Top=seq(5,100,by=5)

Author(s)

Olajumoke Evangelina Owokotomo, [e-mail]

Ziv Shkedy

See Also

CVPcaPls, SurvPcaClass, SurvPlsClass

Examples

## GENERATE SOME METABOLIC SURVIVAL DATA WITH PROGNOSTIC FACTORS
Data<-MSData(nPatients=100,nMet=150,Prop=0.5)

## FIRST IS THE NETABOLITE BY METABOLITE ANALYSIS
w = CVMetSpecificCoxPh(Fold=3,Survival=Data$Survival,
Mdata=t(Data$Mdata),Censor= Data$Censor,Reduce=TRUE,
Select=150,Prognostic=Data$Prognostic,Quantile = 0.5,Ncv=3)

## USING THE FUNCTION
Result = CVSimet(w, Top = seq(5, 100, by = 5), Survival=Data$Survival,
 Censor=Data$Censor, Prognostic = Data$Prognostic)

## GET THE CLASS OF THE OBJECT
class(Result)     # A "cvsim" Class

##  METHOD THAT CAN BE USED FOR THE RESULT
show(Result)
summary(Result)
plot(Result, type =2)

MetabolicSurv documentation built on June 11, 2021, 9:06 a.m.