normalize_timecourse: Normalizes a time course using a given mapping from...

In MultIS: Reconstruction of Clones from Integration Site Readouts and Visualization

Description

Each integration site is replaced by its clone. The size of the clone is adjusted to be the mean size of the integration sites within it. For integration sites that are not mentioned in 'rec', we adjust by the average number of integration sites per clone.

Usage

normalize_timecourse(readouts, rec, rec_first = FALSE, reduce_clones = TRUE)

Arguments

readouts	The integration site readouts to adjust.
rec	A matrix with columns "IS" and "Clone" that assigns each integration site to a clone.
rec_first	Whether the clones should be put in the first rows of the resulting time course.
reduce_clones	Whether to represent the integration sites by their respective clone.

Value

The adjusted time course.

MultIS documentation built on Aug. 6, 2021, 5:07 p.m.