NMwriteInits: Writes a parameter values to a control stream

In NMdata: Preparation, Checking and Post-Processing Data for PK/PD Modeling

Writes a parameter values to a control stream

Description

Edit parameter values, fix/unfix them, or edit lower/upper bounds.

Usage

NMwriteInits(
  file.mod,
  update = TRUE,
  file.ext = NULL,
  ext,
  values,
  newfile,
  ...
)

Arguments

file.mod	Path to control stream.
update	If 'TRUE' (default), the parameter values are updated based on the '.ext' file.
file.ext	Optionally provide the path to an '.ext' file. If not provided, the default is to replace the file name extention on 'file.mod' with '.ext'. This is only used if 'update=TRUE'.
ext	Not implemented.
values	A list of lists. Each list specifies a parameter with named elements. Must be named by the parameter name. 'lower', 'upper' and 'fix' can be supplied to modify the parameter. See examples. Notice, you can use '...' instead. 'values' may be easier for programming but other than that, most users will find '...' more intuitive.
newfile	If provided, the results are written to this file as a new input control stream.
...	Parameter specifications. See examples,

Details

Limitations:

• lower, init, and upper must be on same line

• If using something like CL=(.1,4,15), two of those cannot be on the same line

Value

a control stream as lines in a character vector.

Examples

## Requires NMdata 0.1.9
## Not run: 
file.mod <- system.file("examples/nonmem/xgxr021.mod",package="NMsim") 
NMwriteInits(file.mod,
values=list( "theta(2)"=list(init=1.4),
             "THETA(3)"=list(FIX=1),
             "omega(2,2)"=list(init=0.1))
)
NMwriteInits(file.mod,
  "theta(2)"=list(init=1.4),
  "THETA(3)"=list(FIX=1),
  "omega(2,2)"=list(init=0.1)
)

## End(Not run)

NMdata documentation built on April 4, 2025, 2:11 a.m.