Description Usage Arguments Value Author(s) References See Also Examples
The function is plotting the observed data points of the gene expression and isotonic means with respect to dose for one particular gene.
1 | plotIsomeans(monoData, obsData, doseData, geneIndex)
|
monoData |
isotonic means with respect to dose for all genes |
obsData |
observed gene expression for all genes |
doseData |
indicates the dose levels |
geneIndex |
index of the gene to be plotted |
Plot of the data points and the isotonic means for each dose with the isotonic regression curve.
Adetayo Kasim, Martin Otava and Tobias Verbeke
Lin D., Shkedy Z., Yekutieli D., Amaratunga D., and Bijnens, L. (editors). (2012) Modeling Dose-response Microarray Data in Early Drug Development Experiments Using R. Springer.
Cheng, Y. and Church, G. M. (2000). Biclustering of expression data. In: Proceedings of the Eighth International Conference on Intelligent Systems for Molecular Biology, 1, 93-103.
1 2 3 4 5 6 7 8 9 10 | data(doseData)
data(geneData)
dirData <- monotoneDirection(geneData = geneData,doseData = doseData)
incData <- as.data.frame(dirData$incData)
obsIncData <- as.data.frame(dirData$obsincData)
## gene-specific profile plot
plotIsomeans(monoData=incData,obsData=obsIncData,doseData=
doseData,geneIndex=10)
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