Description Usage Arguments Value Author(s) References

Returns the log-maximum likelihood and the estimator of the mean under the monotone decreasing profile.

1 | ```
decreasing(data,x,n.rep)
``` |

`data` |
A vector containing the expressions of one gene. |

`x` |
A vector consisting of the average expression at time points (1, 2,... ,T), where T is the total number of time points. |

`n.rep` |
A vector consisting of the number of replicate arrays at time points (1, 2,... ,T), where T is the total number of time points. |

`logelr` |
Log-maximum likelihood |

`mu` |
A vector containing the estimator of the mean |

Tianqing Liu, Nan Lin, Ningzhong Shi and Baoxue Zhang

Maintainer: Tianqing Liu <[email protected]>

Liu, T., Lin, N., Shi, N. and Zhang, B. (2009), *Information criterion-based clustering with order-restricted candidate profiles in short time-course microarray experiments.* BMC Bioinformatics, **10**: 146.

Robertson, T., Wright, F. T. and Dykstra, R. L. (1988). *Order restricted statistical inference.* New York: Wiley.

Shi, N., Gao, W. and Zhang, B. (2001). *One sided estimation and testing
problems for location models from grouped samples.*
Commun Statist-Simula, **30**: 885-898.

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