OncoBayes2: Bayesian Logistic Regression for Oncology Dose-Escalation Trials

Bayesian logistic regression model with optional EXchangeability-NonEXchangeability parameter modelling for flexible borrowing from historical or concurrent data-sources. The safety model can guide dose-escalation decisions for adaptive oncology Phase I dose-escalation trials which involve an arbitrary number of drugs. Please refer to Neuenschwander et al. (2008) <doi:10.1002/sim.3230> and Neuenschwander et al. (2016) <doi:10.1080/19466315.2016.1174149> for details on the methodology.

Package details

AuthorNovartis Pharma AG [cph], Sebastian Weber [aut, cre], Lukas A. Widmer [aut], Andrew Bean [aut], Trustees of Columbia University [cph] (R/stanmodels.R, configure, configure.win)
MaintainerSebastian Weber <sebastian.weber@novartis.com>
LicenseGPL (>= 3)
Version0.8-9
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("OncoBayes2")

Try the OncoBayes2 package in your browser

Any scripts or data that you put into this service are public.

OncoBayes2 documentation built on July 26, 2023, 5:30 p.m.