Aims at detecting single nucleotide variation (SNV) and insertion/deletion (INDEL) in circulating tumor DNA (ctDNA), used as a surrogate marker for tumor, at each base position of an Next Generation Sequencing (NGS) analysis. Mutations are assessed by comparing the minor-allele frequency at each position to the measured PER in control samples.
|Author||Yves Rozenholc, Nicolas Pécuchet, Pierre Laurent-Puig|
|Date of publication||2016-09-09 10:13:42|
|Maintainer||Yves Rozenholc <email@example.com>|
|License||MIT + file LICENSE|
background_error_rate: The package provide the SNV and INDEL PERs computed for the...
BuildCtrlErrorRate: function BuildCtrlErrorRate
DetectPlasmaMutation: function DetectPlasmaMutation
hotspot: The package provide a list of known hotspot positions located...
MAF_from_BAM: function MAF_from_BAM
positions_ranges: The package provide the positions and ranges computed for the...
PrepareLibrary: function PrepareLibrary